Tadalista 20mg is a product of tadalafil 20mg. The current treatments include sildenafil, vardenafil, and avanafil. All are phosphodiesterase Type 5 (PDE 5) inhibitors, working with similar action mechanisms. All treatments focus on improving blood flow in the male organ and causing erection. However, the latest research says the action mechanism can go through the brain. Let us delve deeper.
Melanocortin Activators
It works through the central nervous system (CNS) and the brain. Research shows that when applied, they can cause erection in animals. The drug (PT-141), when given intranasal (through the nose) in men, can produce results to address the non-medical, psychological, and emotional causes rather than addressing the physical erectile dysfunction causes. Although it is an outcome of the initial study stage, we need broader studies to ensure the safety and efficacy of the drug.
Gene Therapy
It is a novel therapy. It would provide the genes that will produce products or proteins facing impairment and dysfunction in the erectile tissues (corpus cavernosa) in the penile region of men with ED. Replacing these proteins may improve the ED condition and function. Studies in animals applying gene therapy improved the condition of erectile dysfunction in them. In clinical trials, the doctors inject the modified genes into the penile tissues to augment the blood flow and improve erectile function. We hope human studies show similar successful improvement. However, even if it works, it will take longer for approval from regulatory bodies and public acceptance.
Stem Cell Therapy
These experiments are promising and aim at long-term treatment of ED. This treatment uses stem cells to regenerate impaired penile erectile tissues. Stem cell therapy involves transferring stem cells of the self or a donor to repair and renew the damaged endothelial cells and erectile tissues in the penile region. Doctors may inject these cells directly into the male organ, or the patient can receive them through intravenous (IV) infusion. The success depends on the stem cell donor, and the success has been inconsistent.
Platelet-rich Plasma
Platelets are fragments of cells in the blood. Doctors use them to heal wounds and grow new blood vessels. Often called the “P-shot,” doctors derive PRP from the patient’s blood and inject it into the male organ to activate tissue regeneration and increase the blood flow in the penile region, causing erection. However, studies have not been promising, as they showed no or little improvement in using PRP therapy to treat ED.
Shockwave Therapy
It is a non-invasive technique when the medications do not produce the desired results. Many sexologists are using this treatment already. The therapy applies low-intensity shock waves to improve the blood flow in the tissues of the male organ. A lack of blood flow in the arteries of the corpus cavernosa is a primary cause of ED. A mild shockwave can stimulate the production of new blood vessels, which will increase blood flow and cause erection.
Testosterone Replacement Therapy (TRT)
The application aims at improving low testosterone, which might cause erectile dysfunction. The treatment to replenish testosterone deficiency is through intramuscular injections administered between two to ten weeks apart. The other methods include testosterone gel applied to the skin or inside the nose, Mucoadhesive material above the teeth twice daily, Long-acting subcutaneous pellet, oral (taken by mouth) medications, and Testosterone stick applied like underarm deodorant). Each method replaces the testosterone hormone adequately. This therapy has multiple side effects that you need to deal with under supervision.
Eroxon Gel
The latest treatment the FDA has approved is an over-the-counter (OTC) gel, an alternative to oral ED medications. When applied, with its cooling and warming sensation, it may boost the blood flow in the penile region, causing an erection. Directly apply the gel on the penile glans/head and massage gently for 15 seconds. You must feel the sexual arousal for the gel to take its effect. It works better when your partner applies and massages. Relax mentally and start with foreplay.
Take a small tube content firmly onto your female partner’s fingers for her to massage it on the penis glans. Within a few minutes during the foreplay, the gel will take its effect and cause an erection. The gel also increases the rush of blood flow in the erectile tissues to trigger erection. The gel may cause mild to moderate pain, tingling, warmth, and burning sensations.
Conclusion
If uncomfortable with the above methods, administer the tried and tested treatments with oral medications. Start with the lowest dosage of oral medications that help increase blood flow to your penis, including sildenafil, vardenafil, tadalafil (Tadalista 20mg), or avanafil Ed treatments.
