The active constituent, Avanafil was approved by the FDA in 2012 and by EMA in 2013. It is a PDE-5 inhibitor with a rapid onset of action of 15 minutes. It acts by impeding the action of a specific phosphodiesterase type 5 enzyme present in abundance inside the penile region. The molecular formula of Avanafil is C23H26ClN7O3 and the molecular weight is 483.95g/mol. This medication has a rapid onset of action of about 15 minutes. The maximum concentration is observed in 30 to 45 minutes.
Avanafil, the active component of Stendra Generic inhibits the cGMP specific phosphodiesterase type 5 (PDE5), present in abundance inside the penile region. Penile erection is a result of sexual stimulation produced by improved blood flow to the penile organ due to the dilation of the blood vessels and relaxation of the smooth muscles. This reaction is facilitated by the release of nitric oxide (NO), which is responsible for triggering the synthesis of cGMP. cGMP dilates the blood vessels and relaxes the smooth muscles.
The most commonly witnessed side effects of this medication are as follows-
These side effects usually subside after the drug is eliminated from the body. But, in case, any of these side effects persist over a long duration or worsen with time, immediately call your healthcare provider.
Stop using this medication at once if you experience a sudden loss of vision.
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