The exact mechanism of action of tretinoin is unknown, but research suggests that topical tretinoin helps in reducing the cohesiveness of follicular epithelial cells. It also helps in reducing microcomedo formation. Besides, tretinoin stimulates mitotic activity in the skin, increasing turnover of follicular epithelial cells and causing extrusion of the comedones or acne.
These are common side effects of A-Ret Gel 0.1%, which may occur during the first 2 to 4 weeks of using it. These side effects usually subside after some time. If any of these side effects persist or worsen, see your doctor promptly.
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