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Modanil (Modafinil) Helps in Treating Sleep Apnea, Narcolepsy

Modanil (Modafinil) Helps in Treating Sleep Apnea, Narcolepsy

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Modanil is a stimulant drug marketed as a 'wakefulness promoting agent' and is one of the stimulants used in the treatment of narcolepsy. Narcolepsy is caused by dysfunction of a family of wakefulness-promoting and sleep-suppressing peptides, the orexins, whose neurons are activated by Modanil. The prexin neuron activation is associated with psychoactivation and euphoria.

The exact mechanism of action is unclear, although in vitro studies have shown it to inhibit the reuptake of dopamine by binding to the dopamine reuptake pump, and lead to an increase in extracellular dopamine. Modanil activates glutamatergic circuits while inhibiting GABA.

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Advantages of Modanil Tablet:

  • Modanil 100Mg Tablet 10'S belongs to the category of the stimulant indicated to improve wakefulness in persons who feel very sleepy due to narcolepsy.
  • It works by increasing the amount of a chemical known as dopamine in the brain by reducing the reabsorption of dopamine into nerves.
  • Dopamine is a chemical neurotransmitter that is used by nerves to send signals for communication purposes.
  • In this way, it helps a person to stay awake during their office hours or for performing normal activities of the day and to have a normal sleep routine.

Working of Modanil Tablet:

It works by enhancing the amount of a chemical messenger known as 'dopamine' in the brain which controls the sleep-wake cycle of our body. It reduces the reuptake of dopamine into nerves. Dopamine is a chemical neurotransmitter that is used by nerves for communication purposes.

Dosages of Modanil Tablet:

Usual Adult Dose for Narcolepsy:

  • 100 mg orally daily in the morning
  • Usual Adult Dose for Obstructive Sleep Apnea/Hypopnea Syndrome:
  • 100 mg orally daily in the morning
  • Usual Adult Dose for Shift Work Sleep Disorder:
  • 100 mg orally daily one hour prior to the start of the work shift

    Precautions of Modanil Tablet:

  • You should not use this medication if you are allergic to Modanil or armodafinil (Nuvigil).
  • if you have any of these other conditions, tell your doctor: angina (chest pain); cirrhosis or other liver problem; kidney disease; a heart muscle or valve disorder such as mitral valve prolapse; a history of drug addiction; if you take blood pressure medications; or if you have recently had a heart attack.
  • Skin rashes serious enough to require hospitalization have occurred in people using a medicine similar to Modanil. These rashes usually occurred within 1 to 5 weeks after the first dose.

Side Effects of Modanil Tablet:

Like other drugs, Modanil 100Mg Tablet 10'S may cause some unpleasant effects, however, some of its undesirable effects do not require medical attention. The most common side effects include

  • Headache
  • Diarrhea
  • Back pain
  • Feeling anxious
  • Nausea
  • Trouble sleeping
  • Feeling nervous
  • Dizziness
  • Stuffy nose
  • Upset stomach.

Warnings of Modanil Tablet:

  • A person should tell their doctor straight away if they are feeling depressed, aggressive towards other people.
  • Tell your doctor if your using Hormonal contraceptives like contraceptive pills as Modanil 100Mg Tablet 10'S can reduce their effectiveness and increase the chances of pregnancy.
  • A pregnant or breastfeeding women should not use Modanil 100Mg Tablet 10'S without asking the doctor as this medicine can cause birth defects during pregnancy and can pas in breastmilk as well.
  • This medicine contains lactose so tell your doctor if you have an intolerance to some sugars. This is a habit-forming medicine so do not change the dose or use it for a longer time without asking the doctor.

FAQs

In some cases, it always advisable to stop the intake of some medicines gradually because of the rebound effect of the medicine. It's wise to get in touch with your doctor as a professional advice is needed in this case regarding your health, medications and further recommendation to give you a stable health condition.
Before using Modanil, tell your doctor if you are using any of the following drugs: cyclosporine (Neoral, Sandimmune, Gengraf); propranolol (Inderal); rifampin (Rifadin, Rimactane, Rifater); a sedative such as diazepam (Valium), midazolam (Versed), or triazolam (Halcion);

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